CAS Google Scholar. Once the roots have established, adjust watering to three to five days apart. They protect our cells from the harmful effects of reactive oxygen species. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. Olumese FE, Onoagbe IO, Eze GI, Omoruyi FO. However, lowest (50mg/kg) dose of extract significantly elevated MCH and MCHC. Rich on haematological and biochemical parameters in healthy Wistar rats. Adetuyi is a Professor of Biochemistry in the Department of Chemical Sciences, Faculty of Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Extinction coefficient () of MDA TBA complex=1.56105M1cm1. aqueous extract J. carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male Wistar albino rats. Fertility leaves: Benefits and side effects, Guava Leaf Tea: Health Benefits of Guava Leaves, Coriander seeds: 18 benefits Coriandrum sativum fruits and seeds, Rapini: Nutritional facts, benefits, side effects and care. Clinical Guide to Laboratory tests. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. Ethnomedical study and iron content of some medicinal herbs used in traditional medicine in cote divoire for the treatment of anaemia. Grows up to 4-6 ft. tall (120-180 cm) and 2-3 ft. wide (60-90 cm). Effects of kolaviron on hepatic oxidative stress in streptozotocin induced diabetes. A cup of water 2012; 22(1):220238; https://doi.org/10.1590/S0102-695X2011005000196. Mounanga MB, Mewonob L, Angone SA. These tropical plants are not very fussy about soil. Acta Sci Pol Technol Aliment. Be sure to follow relevant directions on product labels and consult your, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Watering depends on humidity and temperature. Total reaction mixture of 3ml contained 2.95ml of 0.05M sodium carbonate buffer (pH10.2), 0.02ml tissue sample and 0.03ml of epinephrine (2mM) in 0.005N HCl was used to initiate the reaction. However, there have not been scientific backing on this claim, yet, from the antiviral properties of other species of justicia, it could be that this plant possess antiviral properties which is utilized in the treatment of hepatitis infection. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. Mr. T.S. 2010;32(1):1328 https://doi.org/10.3109/08860220903367585. Uses, Benefits, Cures, Side Effects, Nutrients in Justicia Betonica. Locklear, T. D., Huang, Y., Frasor, J., Doyle, B. J., Perez, A., Gomez-Laurito, J., and Mahady, G. B. Estrogenic and progestagenic effects of extracts of Justicia pectoralis Jacq., an herbal medicine from Costa Rica used for the treatment of menopause and PMS. Ewe eje as it is fondly called by the Westerners in Nigeria is a plant known for its blood boosting abilities. Cookies policy. In various parts of Africa, several species of Justicia are used in traditional medicine for the treatment of anemia, inflammation, fever, diarrhea, liver diseases and arthritis respiratory and gastrointestinal disorder [8, 9]. Ewe eje is safe and healthy for consumption. The animals were initially examined for any signs of toxicity after 60min of administration and further observed for a period of 24h. The absence of rat mortality in phase I necessitated the conduct of the second phase. The flowers are slightly fragrant and mostly sterile. Ethanol extracts of J. carnea leaf increased RBC, hemoglobin and platelet with significant increase (p<0.05) in groups that received higher dose (>500mg/kg b.w) of extract compared to the control. Each of the rats received 1500, 2900 and 5000mg/kg body weight of JCEE respectively and examined within 24h for manifestation of toxicity. Pinch out tips to promote compact plants. 2023 BioMed Central Ltd unless otherwise stated. 2005 - 2023 WebMD LLC, an Internet Brands company. The unique flower clusters and bright coloring has made it a popular choice among landscape artists and amateur gardeners as well. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. Mapanga RF, Musabayane CT. The Pros and Cons of Creatine You Should Know. A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. Not sure which Justicia to pick?Compare All Justicia. Liver superoxide dismutase (SOD) activity was significantly (p<0.05) increased at 1200mg/kg while other tested doses caused no detrimental effect on glutathione, catalase, SOD and malondialdehyde level in liver and kidney. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. At the end of the 14th day of administration, the rats were allowed to fast overnight and sacrificed the following morning by anesthetizing each rat in a closed chamber containing drops of chloroform. Cover and leave for about fifteen minutes. While the renal tubules across the tested groups were normal with the interstitial spaces showing moderate congestion and hemorrhage, there appeared some abnormalities in the renal cortex (such as few sclerotic glomeruli with moderately dilated capsular spaces) resulting in fair architectural structure of the kidney (Fig. 200, 500 and 1000 mg/kg bw of Justicia carnea showed a significant (p<0.05) decrease in the activities of ALT, AST and ALP, and bilirubin level while total protein and albumin levels increased significantly (p<0.05) when compared with the rats treated with CCl alone. Create a membership account to save your garden designs and to view them on any device. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. As a consequence, depletion of reduced glutathione (GSH) either by removal from the cell or oxidation to GSSG could eventually lead to mild oxidative stress in cells and tissues [33, 34]. 2016;5(1):6270 https://doi.org/10.1016/j.joad.2015.08.006. The resultant liquid after boiling is usually crimson red. This is . This is in agreement with study of Anthonia et al., [21] who obtained LD50 above 5000mg/kg for aqueous extracts of J. carnea leaf. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. This information may not fit your specific health circumstances. Treatments of all experimental animals were performed following Principle of Laboratory Animal Care manual guidebook of National Institute of Health as approved by the Research Ethics Committee of Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State. J Ethnopharmacol. The plants cannot be propagated with seeds. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. The mixture was incubated at 28C for 30min and the absorbance read at 550nm against the reagent blank. Why urban citizens in developing countries use traditional medicines: the case of suriname. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Technical guidelines assembly of veterinary medicine research. Leaf extract in isoproterenol induced myocardial infarction in albino rats. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. The plant looks great along garden borders and near building foundations. View abstract. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). Author ESA managed the literature searches and wrote the first draft of the manuscript with the assistant of FOA. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. The significant decrease in kidney GSH at 1200mg/kg could be due to ample dietary bioactive constituents in the extract that requires frequent conjugation of GSH in the cell or oxidation to oxidized glutathione (GSSG). This may be because of its hepatoprotective activity. J Med Plants Res. 2008; 10:2. 1978;90:819. Pharm. McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. It creates the perfect environment for aphids and dried sod. Background: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. Nunes TRS, Cordeiro MF, Beserra FG, et al. Superoxide dismutase was carried out using the method of Sun and Zigma [18]. 3 The plants in the family are reported to have CNS effects which are exploited in the management of epilepsy, other mental disorders, headache and fever, probably due to their sedative and analgesic properties. Hence, Justicia carnea can be used to strengthen the immune system. The red coloration of the decoction made people think that the plant must contain blood boosting compounds. Clin Phytosci 7, 2 (2021). The renal effects of blood glucose-lowering plant-derived extracts in diabetes mellitus-an overview. Rich, well-drained soil retaining ample moisture is the perfect home for Brazilian plume flowers. This study investigated the in-vitro antioxidant activity of ethanol leaf extract of Justicia carnea and its effect on antioxidant status of alloxan-induced diabetic albino rats. 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. leaf inhibits interferon-γ secretion and has bacteriostatic activity against Acinetobacter baumannii and Klebsiella pneumoniae. In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. Anal Biochem. Join now and start creating your dream garden! Two of the most important soil considerations include fertility and drainage. He has B.Sc.,and M.Sc. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. Leal, L. K., Ferreira, A. With exception of low doses that showed normal morphology of the hepatocyte and sinusoid that is not infiltrated, high doses of extract greater than 500mg/kg showed mild fat congestion in the central venules with liver parenchyma showing area of hemorrhage compared to the control. From mild to severe order, the graded doses showed distorted renal cortex with collapsed renal glomeruli and dillated capsular spaces. CAS Water your plants deeply during growth periods, allowing the soil to dry . -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking.
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